Sodium Caseinate

Product Details :

Description:

BSA and casein are used to block non-specific protein binding. Casein is cheaper than BSA and is suitable for most applications, However, I do know of at least one application were casein is NOT suitable as a blocking agent, and that is for detecting anti-phosphoryl choline antibodies in ELISA. The reason for this is that casein is derived from milk - most typically spoiled or out-of-date milk - and has significant amounts of bacterial debris present, which includes many different bacterial antigens, notably teichoic acids, which often contain phosphoryl choline. My guess is that whatever antibody you are using for whatever application, it cross-reacts with some bacterial antigens found in casein, thereby obstructing your assay.

Additional Information:

• Item Code: SC
• Production Capacity: 1000000
• Delivery Time: 2-4 weeks