Sm Antigen ELISA

Product Details :

Smith Antigen summarizes core proteins of the U1-snRNP complex. The U1-snRNP is part of the splicosomal complex, that facilitates the processing of the pre mRNA to mature mRNA in the nucleus. Antibodies against Sm belong to a heterogeneous group of ANA which are associated with various autoimmune diseases. Anti Sm antibodies are highly specific for SLE and are thus included in diagnostic and classification criteria for SLE.

Our kit is calibrated against reference sera from CDC, Atlanta.